John Crowley

John F. Crowley is the President and CEO of the Biotechnology Innovation Organization (BIO), the world’s largest biotechnology advocacy organization. Crowley, a longtime BIO board member, was most recently the Founder and Executive Chairman of Amicus Therapeutics, a global biotechnology company focusing on developing treatments for rare genetic diseases. He served as Chief Executive Officer of Amicus from 2005 to 2022.

Crowley’s decades of biotech experience and deep passion for the field have made him a strong supporter of policies that empower innovation, enable entrepreneurship, and put people and patients first. His involvement with biotechnology stems from the 1998 diagnosis of two of his children with Pompe disease -- a severe and often fatal neuromuscular disorder. In his drive to find a cure for them, Crowley left his position at Bristol Myers Squibb and became an entrepreneur as the co-founder, President and CEO of Novazyme Pharmaceuticals, a biotech start-up conducting research on a new experimental treatment for Pompe disease (which he credits as ultimately saving his children’s lives). In 2001, Novazyme was acquired by Genzyme Corporation, where Crowley continued to play a lead role in the development of a drug for Pompe disease as Senior Vice President, Genzyme Therapeutics.

Crowley and his family have been profiled numerous times on the front page of The Wall Street Journal and are the subjects of a book by Pulitzer Prize-winning journalist Geeta Anand, “The Cure: How a Father Raised $100 Million -- And Bucked the Medical Establishment -- In a Quest to Save His Children.” The 2010 major motion picture, "Extraordinary Measures," starring Brendan Fraser, Harrison Ford and Keri Russell, is inspired by the Crowley family journey. Crowley is the author of a personal memoir “Chasing Miracles: The Crowley Family Journey of Strength, Hope, and Joy.”

Crowley served as a commissioned officer in the U.S. Navy Reserve from 2005-2016. He is a veteran of the global war on terrorism, with service in Afghanistan. His assignments included service with the Joint Special Operations Command, the Naval Special Warfare Development Group and the Central Intelligence Agency. Crowley attended the U.S. Naval Academy and went on to earn a BS in Foreign Service from Georgetown University, a JD from the University of Notre Dame Law School, and an MBA from the Harvard Business School.

The Crowley family was the recipient of the 2011 Family Exemplar Award from the University of Notre Dame. Crowley is also a member of the University Council on Science & Technology at Notre Dame and serves on the Board of Directors of the United States Naval Academy Foundation. He is the former National Chairman of the Make-A-Wish Foundation of America and served on the board of BioNJ. Crowley is a Henry Crown Fellow at the Aspen Institute. He was awarded a Doctor of Laws Degree (Honoris Causa) from the University of Notre Dame, where he delivered the commencement address to the Class of 2020. In 2023, he was inducted as a member of the Horatio Alger Association.