John C. York II (born 1950 in Muskogee, Oklahoma) is the co-owner of the San Francisco 49ers, along with wife Denise DeBartolo York.
York attended the University of Notre Dame, studying pre-medicine. While in college, he met his wife, who was attending the neighboring St. Mary's College of Indiana. He earned his medical degree from Loyola University and did residency training at Vanderbilt University. He has become a renowned cancer pathologist and often lectures on his work at elite universities.
In 1982, York founded DeYor Laboratories, a small research company that has eventually grown to become a corporation of over 500 employees. It has been absorbed into his wife's company, The DeBartolo Corporation, of which York is executive vice president.
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