Nathalie Kelley

In 2005, Charmed executive producers Brad Kern, Aaron Spelling and E. Duke Vincent developed a one-hour pilot for The WB titled Mermaid. Kelley was cast as the series protagonist Nikki, a mermaid who is rescued by a young man when she washes ashore in Miami. The pilot was not picked up as a result of The WB and UPN merging into The CW; the resulting network passed on the show. Kelley has since appeared on both Lone Star and CSI: Crime Scene Investigation.

In June 2006, Kelley received her breakout role as Neela in the film The Fast and the Furious: Tokyo Drift, the third installment of The Fast and the Furious franchise. In March 2008, Kelley appeared in the low-budget drama crime film Loaded alongside Jesse Metcalfe. In March 2011, Kelley had a small role in the retro comedy film Take Me Home Tonight, which starred Topher Grace, Anna Faris and fellow Australian Teresa Palmer. The film was shot in Los Angeles in 2007 but its release was delayed by Universal Pictures for unknown reasons. The following month, Kelley appeared as the protagonist in the low-budget horror film Urban Explorer, which follows a group of four urban explorers who explore an underground world beneath metropolitan Berlin.

In 2010, Kelley played the love interest in the music video for the Bruno Mars song "Just the Way You Are". In August 2011, Kelley signed on in a major recurring role in the second season of the ABC crime drama television series Body of Proof. Kelley appeared as Dani Alvarez in ten episodes and made her final appearance in the episode "Going Viral Part One". In 2012, Kelley played a vampire princess in the video clip "Luna Llena" from Puerto Rican reggaeton duo Baby Rasta & Gringo. In 2014, she won a regular role in the Lifetime series Unreal. In January 2017, Kelley was cast as Cristal in The CW's Dynasty reboot.