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Sonia Vallabh

Prion Scientist & Senior Group Leader at Broad Institute

Sonia Vallabh
Travels From Travels From:
Cambridge, MA, USA
Speaking Fee Speaking Fee:
Live Event: Please Contact
Virtual Event: $5,000 - $10,000
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Categories Categories:
Categories Categories:
Genetics, Health, Healthcare, Medicine, Neuroscience, Research & Exploration, Science, STEM, Women's Health
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Sonia Vallabh Biography

Sonia Vallabh co-leads the initiative to develop preventive drugs for prion disease at the Broad Institute. She comes to this work with a personal mission. In 2010, Vallabh watched her 52-year-old mother die of a rapid, mysterious, undiagnosed dementia. One year later, Vallabh learned that her mother’s disease had been genetic prion disease, and that she herself was at risk. Vallabh underwent predictive genetic testing and learned that she had inherited the causal mutation, placing her at very high risk of developing the same disease. There was no prevention, treatment, or cure available. Vallabh quit her previous career in law and consulting, and, together with her husband, Eric Minikel, re-trained as a scientist in order to devote her life to finding a way to stop her disease before it starts.

At the Broad, Vallabh is focused on developing preventive drugs for prion disease. Lowering of prion protein (PrP) is a genetically well-validated strategy for delaying the onset of prion disease, and it lends itself to measurement of PrP as a biomarker available before the disease process has begun. Vallabh is working on the discovery and preclinical development of PrP-lowering drugs, credentialing of PrP in cerebrospinal fluid as a pharmacodynamic biomarker for such drugs, and establishment of a clinical pathway for preventive drug development. She co-leads a natural history study at Massachusetts General Hospital devoted to the assessment of fluid biomarkers in individuals at risk for genetic prion disease, and helped to launch the Prion Registry to promote and enable research participation in her community.

Vallabh holds a B.A. from Swarthmore College, a J.D. from Harvard Law School, and a Ph.D. in Biological and Biomedical Sciences from Harvard University. She trained in Stuart Schreiber’s laboratory at the Broad. In 2016, she served as a patient representative in the White House Precision Medicine Initiative. Her story has been told in The New Yorker, NPR, and WIRED.

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Sonia Vallabh Videos

  • My Quest to Cure Prion Disease — Before It’s Too Late | Sonia Vallabh | TED
    My Quest to Cure Prion Disease — Before It’s Too Late | Sonia Vallabh | TED
    Biomedical researcher Sonia Vallabh's life was turned upside down when she learned she had the genetic mutation for a rare and fatal illness, prion...
  • A genetically informed paradigm for primary prevention of prion disease
    A genetically informed paradigm for primary prevention of prion disease
    There are few stories in science more inspiring than that of Dr Sonia Vallabh and Dr Eric Minikel. After seeing her mother rapidly decline and pass...
See All Videos »

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  • What topics does Sonia Vallabh speak about?

    Sonia Vallabh is a keynote speaker and industry expert whose speaking topics include Genetics, Health, Healthcare, Medicine, Neuroscience, Research & Exploration, Science, STEM, Women's Health.

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    Sonia Vallabh generally travels from Cambridge, MA, USA, but can be booked for private corporate events, personal appearances, keynote speeches, or other performances. For more details, please contact an AAE Booking agent.

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Sonia Vallabh is a keynote speaker and industry expert who speaks on a wide range of topics . The estimated speaking fee range to book Sonia Vallabh for your event is available upon request. Sonia Vallabh generally travels from Cambridge, MA, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Barbara Sturm, Gabriella Rosen Kellerman, Deeptee Jain, Stephanie Lheureux and Kimberly Noble. Contact All American Speakers for ratings, reviews, videos and information on scheduling Sonia Vallabh for an upcoming live or virtual event.

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